500.21 Bad module “ManagedPipelineHandler” in its module list

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ASP.Net  IIS 7  IIS 
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I  am getting the error:
HTTP Error 500.21 - Internal Server Error Handler "CloudConnectHandler" has a bad module "ManagedPipelineHandler" in its module list

my web.config file looks like this:
<?xml version="1.0" encoding="utf-8"?>
      <add name="CloudConnectHandler" verb="*" path="CloudConnect.aspx" type="CloudConnectHandler" resourceType="Unspecified" />
    <customErrors mode="Off" />
    <compilation debug="true" targetFramework="4.0" batch="false">
        <add assembly="System.Xml.Linq, Version=, Culture=neutral, PublicKeyToken=B77A5C561934E089" />
        <add assembly="System.Core, Version=, Culture=neutral, PublicKeyToken=B77A5C561934E089" />
        <add assembly="Microsoft.CSharp, Version=, Culture=neutral, PublicKeyToken=B03F5F7F11D50A3A" />
        <add tagPrefix="ajaxToolkit" assembly="AjaxControlToolkit" namespace="AjaxControlToolkit" />
        <identity impersonate="true" />
        <authentication mode="Forms" />
      <compiler language="c#;cs;csharp" extension=".cs" warningLevel="4" type="Microsoft.CSharp.CSharpCodeProvider, System, Version=, Culture=neutral, PublicKeyToken=b77a5c561934e089">
        <providerOption name="CompilerVersion" value="v4.0" />
        <providerOption name="WarnAsError" value="false" />
    <add key="CloudConnectAuthorization" value="xxxx" />
    <add key="ConnectionInfo" value="xxxx" />
    <add key="ConnectionString" value="xxxx" />
    <add key="DefaultChannel" value="xxxx" />
    <add key="LoginValidationConnectionString" value="xxxx" />
    <assemblyBinding xmlns="urn:schemas-microsoft-com:asm.v1">
        <assemblyIdentity name="protobuf-net" publicKeyToken="257b51d87d2e4d67" culture="neutral" />
        <bindingRedirect oldVersion="" newVersion="" />

There is a lot of advice out there indicating that asp.net is not installed correctly. The usual fix is to run:

%windir%\Microsoft.NET\Framework64\v4.0.30319\aspnet_regiis.exe -i
%windir%\Microsoft.NET\Framework\v4.0.21006\aspnet_regiis.exe -i
I have run both, without any errors. I have restarted IIS, but the problem still persists. The site is using an application pool. The app pool is started, .net framework = 4.0, Managed Pipeline = Classic, Identity = LocalSystem.

I've spent the last couple hours trying to figure out what the problem is. I'm hoping someone can help.
  1. Re: 500.21 Bad module “ManagedPipelineHandler” in its module list

    Try switching to Integrated mode.

    Please follow these steps:
    1) Run the command prompt as administrator.
    2) Type either of the two lines below in the command prompt:
    %windir%\Microsoft.NET\Framework\v4.0.30319\aspnet_regiis.exe -i
    %windir%\Microsoft.NET\Framework64\v4.0.30319\aspnet_regiis.exe -i

      Modified On Apr-10-2018 05:06:48 AM


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