UpdatePanelAnimation Properties:

TargetControlID - ID of the UpdatePanel whose updates are used to play the animations (this is also the default target of the animations)

OnUpdating - Generic animation played as when any UpdatePanel begins updating

OnUpdated - Generic animation played after the UpdatePanel has finished updating

Code:

Add these control on aspx page

 <%-- ScriptManager control manages client script for AJAX enabled ASP.NET pages.This enables partial-page rendering and Web-service calls.You have to used this if you want to use ajax control--%>
<asp:ScriptManagerID="ScriptManager1"runat="server"></asp:ScriptManager>
  
<cc1:UpdatePanelAnimationExtenderID="UpdatePanelAnimationExtender1"runat="server"   TargetControlID="UpdatePanel1">
<Animations>                  
      <OnUpdating>                       
            <Sequence>
<ColorAnimationTarget="Button1" Duration="50" StartValue="#FF0000" EndValue="#666666" PropertyKey="backgroundColor"/>
                  <EnableActionEnabled="true"/>
</Sequence>             
      </OnUpdating>   
 <%--OnUpdating animation will always play when any partial postback starts--%>         
       <OnUpdated>  
            <Sequence>  
                  <Parallelduration="2"Fps="30">  
                        <FadeInAnimationTarget="Button1"/>                              
                   </Parallel>                                  
            </Sequence>             
      </OnUpdated>  
 <%--OnUpdated animation will only play at the end of a partial postback if its UpdatePanel. --%>       
</Animations>
</cc1:UpdatePanelAnimationExtender>
  
  
 
<asp:UpdatePanelID="UpdatePanel1"runat="server">
<ContentTemplate>
<asp:ButtonID="Button1"runat="server"OnClick="Button1_Click"Width="80px" Height="60px"Text="Click Here"/>
<asp:LabelID="Label1"runat="server"></asp:Label>
</ContentTemplate>
<Triggers>
 <asp:AsyncPostBackTriggerControlID="Button1"EventName="Click"/>
</Triggers>
</asp:UpdatePanel>
  
Write these code on Button1 click
protectedvoid Button1_Click(object sender, EventArgs e)
    {
         Label1.Text = DateTime.Now.ToString();
    }

 Run The Project

When you click the click here button then OnUpdating property change color of click her button.

And after information is updated then updated property will work which has been specified  

<FadeInAnimationTarget="Button1"/>